Science

The future of regenerative medicine

At Procelk®, we focus on adult mesenchymal stem cells because of their ability to regenerate tissues, modulate the immune system, and promote cellular recovery. Here, we explain what they are, the different types of stem cells, their therapeutic capabilities, and the rigorous characterization process that ensures the quality and safety of every treatment.

Illustration of mesenchymal stem cells in culture, with their elongated extensions.

Stem cells

What are stem cells?

Stem cells are unique biological units with the extraordinary ability to transform into different types of cells in the human body. Unlike specialized cells, such as muscle or nerve cells, they can regenerate tissues, repair damage, and strengthen the immune system. These properties make them a fundamental tool in regenerative medicine, with enormous potential for the treatment of multiple health conditions.

Cell culture under the microscope: elongated cells with the characteristic shape of mesenchymal stem cells.

Cell origin

Types of stem cells according to their origin

Illustration of red blood cells and platelets.

Embryonic stem cells

Stem cells found in tissue during the earliest stages of embryonic development, with the ability to differentiate into all cell types. However, their use is not considered safe and carries ethical implications.

Adult stem cells

These are stem cells found in different niches of already differentiated or developed tissues. Adult stem cells include mesenchymal and hematopoietic stem cells.

Mesenchymal stem cells

They are found in bone marrow, body fat, or umbilical cord tissue. These cells can repair connective tissues such as bone, cartilage, tendons, and ligaments, making them well suited for joint problems, sports injuries, and more.

Hematopoietic stem cells

These are responsible for the formation of blood cells, which is why they are used in blood-related treatments such as bone marrow transplants or for treating leukemia and anemia.

Our cellular products

Platelet-rich plasma

Platelet-Rich Plasma (PRP) is a concentration of platelets obtained from the patient’s own blood, containing growth factors that stimulate tissue repair and regeneration. PRP helps accelerate and improve cellular regeneration processes, restoring health and vitality to tissues. It is also a safe, minimally invasive treatment used for a variety of medical conditions related to wound healing, joint wear, inflammatory processes, and as a complementary treatment for symptoms caused by degenerative diseases.

Source doi.org/10.1089/ten.TEB.2018.0008

Research

Cellular products in development

CRISPR-CAS9

CRISPR-CAS9 is a gene-editing method that allows precise cuts in DNA to correct, modulate, or improve cellular functions. This has made it an innovative technique that has opened the door to safer, more precise, more effective, and more personalized therapies. It continues to drive research for the treatment of cardiovascular, neurological, metabolic, immunological, and infectious diseases such as HIV, HBV, and HCV, establishing itself as one of the most important tools in modern personalized medicine. It is currently used for the treatment and diagnosis of genetic, infectious, and non-infectious disorders.

Sources doi.org/10.1134/S0006297922080090 doi.org/10.1371/journal.pone.0191709 doi.org/10.1089/hum.2017.25 doi.org/10.1016/j.scr.2016.09.018

Exosomes

Exosomes are small vesicles produced by our own cells that act as messengers, carrying signals that help regulate cellular processes. They are also widely studied for their ability to support a balanced tissue environment, promote regeneration, and modulate inflammation, making them an innovative tool to stimulate the body’s natural restoration processes without the use of cells.

Source doi.org/10.1038/s41392-023-01704-0

Adult mesenchymal stem cells

Why are the stem cells we use the best option?

In our treatments, we use only adult mesenchymal stem cells. These stem cells are a safe, ethical, and effective option in regenerative medicine, since they do not require the use of embryonic cells but still offer strong regenerative potential. They are obtained from tissues such as bone marrow, fat, or umbilical cord tissue, and may come from the patient (autologous) or from a donor (heterologous).

Autologous cells

Because they come from the same patient, they are 100% compatible, reducing the risk of rejection and side effects.

Heterologous cells

When they come from another patient, they do not express HLA (cell identity markers), which makes them broadly accepted by the immune system and allows their use without significant risk of rejection.

Both options have been widely researched and used in safe and effective treatments to regenerate tissues and improve quality of life.

How they work

Therapeutic properties

Stem cells have unique therapeutic properties:

Tissue regeneration

They can transform into several types of specialized cells, such as bone, cartilage, and tendon cells, to repair damaged tissues.

Inflammation reduction

They help modulate inflammation in the body to relieve discomfort from chronic diseases such as arthritis.

Immune system balance

They regulate autoimmune responses and reduce the risk of rejection in transplants.

Improved circulation

They promote the formation of new blood vessels, improving oxygen delivery to affected areas and circulation overall.

Collagen production

They stimulate collagen production, an essential component in skin and cartilage repair.

Stem cells are a powerful tool in regenerative medicine, with great potential not only for treating diseases or injuries, but also for improving general well-being and optimizing health in a comprehensive way.

Stem cells, illustrated

Illustration of stem cells with their extensions, in warm light.Illustration of a single spherical cell suspended in fluid.Illustration of elongated cells forming a network.

Patients

Benefits for patients

Stem cells not only accelerate recovery, but also offer a safe and effective solution for many health conditions.

Prevention and improved quality of life

They are useful not only for treatment, but also for disease prevention, helping maintain a better quality of life over time.

Delayed cellular aging

Their ability to regenerate cells helps slow the effects of aging, improving well-being and physical appearance.

Pain reduction and improved mobility

By reducing inflammation and promoting cellular regeneration, patients may experience less pain and greater flexibility in joints, muscles, and other tissues.

Faster recovery

Stem cells support a quicker and more efficient recovery after injuries or surgeries, helping patients return to daily activities sooner.

Reduced inflammation

Thanks to their anti-inflammatory properties, stem cell treatment may reduce chronic inflammation and improve overall well-being.

Alternative to invasive treatments

Stem cells offer a less invasive option compared with surgical procedures, reducing risks and recovery time.

Treatment for chronic and degenerative diseases

They may serve as a therapy to improve quality of life in people with osteoarthritis, lupus, Alzheimer’s disease, diabetes, and other conditions by helping restore damaged bodily functions and addressing the problem at its source, not just relieving symptoms.

Stem cell treatment not only accelerates recovery, but also offers a safe and effective solution for many health conditions, helping patients live a fuller and more active life.

Quality control

Quality of our cells

At Procelk®, the quality of stem cells is our highest priority. We are committed to offering the most advanced and effective treatments in regenerative medicine, using top-quality stem cells to ensure exceptional results and the best care for our patients.

Thanks to our strategic alliance with CryoHoldco, a leader in stem cell research and cryopreservation, we have access to the purest, highest-quality stem cells. This bank, the largest in Latin America, is dedicated to stem cell preservation and storage under the most rigorous standards, using cutting-edge technologies. CryoHoldco is a global reference in the field of cryopreservation and regenerative therapies. Together, we are transforming the future of medicine by providing access to innovative therapies that can improve health and quality of life. By working with CryoHoldco, we not only ensure stem cell quality, but also guarantee that treatment is backed by top-level scientific and technological research.

At Procelk®, we are proud to offer the latest in regenerative medicine, supported by the most advanced scientific network and the largest, most trusted stem cell bank in Latin America. With our expertise and that of CryoHoldco, each stem cell treatment is an opportunity to transform health and well-being in a safe and effective way.

Researcher examining a sample under the microscope.

Safety

Commitment to excellence and patient safety

At Procelk®, we are dedicated to offering the best in stem cell treatments, ensuring the highest quality and safety in every application. Our process is carefully designed to ensure optimal results and protect the health of our patients.

High-level biosafety

We make sure the stem cells we use are completely free of contaminants and risks, giving patients confidence that their health is protected at all times.

High-precision phenotype

We verify that the cells express specific surface markers, ensuring that they are authentic stem cells and meet the highest scientific standards.

Functional capacity

We carefully evaluate the quality of the cells and their ability to produce the factors needed to fulfill their therapeutic function: restoring the body’s function.

Morphology and rigorous characterization

We analyze the shape and structure of the cells in detail to ensure they meet the expected physical characteristics, preserving quality and therapeutic effectiveness.

Cell count

We use a precise measurement process that allows us to know the number of living cells available, ensuring that we can reach therapeutic goals.

Proven cell viability

We determine the percentage of living, active cells to ensure they are fully functional at the time of application, providing an effective and safe treatment.

Each step is designed to offer the best in quality and safety, with a comprehensive approach that prioritizes patient well-being. Trust us to provide cutting-edge stem cell treatment backed by science and experience.

Laboratory staff opening a liquid nitrogen tank, with vapor rising from the container.
Cryopreservation at the Procelk laboratory.

Next step

Are you ready to transform your health?

Find out whether you are a candidate for personalized regenerative therapy.